Gland segmentation based on morphological clues and feature fusion

The task of gland segmentation based on deep learning serves as a crucial auxiliary tool for diagnosing cancer. However, existing methods still exhibit shortcomings in handling gland adhesion and scale adaptability. To address these issues, we propose a gland segmentation approach that leverages morphological cues and multi-level feature fusion. By analyzing the morphological and imaging characteristics of glands, we have devised a novel scheme for label generation and loss weighting to guide model training. This scheme helps alleviate the challenge posed by the presence of adjacent glands and their adhesion. Additionally, by exploring the correlation between semantic features at different levels, we have developed a new feature fusion mechanism to mitigate issues related to model inaccuracies arising from variations in gland scales. Through experimental comparisons and discussions with classical and state-of-the-art methods, we demonstrate the effectiveness of our proposed approach.