Impedance-based Detection of Blood Clotting Time

This paper investigates the electrical properties of porcine blood, blood clot, and serum samples by measuring their absolute conductivity across frequency. At 1 kHz, the measured conductivity of blood is 0.44 S/m, blood clot is 0.34 S/m, and serum is 1.50 S/m. An impedance marker is identified to measure blood clotting time, demonstrated by varying the concentration of Ca
²⁺
added to initiate clotting. The study accounts for blood drying, serum in the measurement chamber, and electrode parasitics. This research provides a foundation for further exploration and validation of the impedance-based approach in measuring blood clotting time and erythrocyte sedimentation rate to improve clinical practice and advance coagulation monitoring.