Improving VTE Identification through Adaptive NLP Model Selection and Clinical Expert Rule-based Classifier from Radiology Reports

Rapid and accurate identification of Venous thromboembolism (VTE), a severe cardiovascular condition including deep vein thrombosis (DVT) and pulmonary embolism (PE), is important for effective treatment. Leveraging Natural Language Processing (NLP) on radiology reports, automated methods have shown promising advancements in identifying VTE events from retrospective data cohorts or aiding clinical experts in identifying VTE events from radiology reports. However, effectively training Deep Learning (DL) and the NLP models is challenging due to limited labeled medical text data, the complexity and heterogeneity of radiology reports, and data imbalance. This study proposes novel method combinations of DL methods, along with data augmentation, adaptive pre-trained NLP model selection, and a clinical expert NLP rule-based classifier, to improve the accuracy of VTE identification in unstructured (free-text) radiology reports. Our experimental results demonstrate the model’s efficacy, achieving an impressive 97% accuracy and 97% F1 score in predicting DVT, and an outstanding 98.3% accuracy and 98.4% F1 score in predicting PE. These findings emphasize the model’s robustness and its potential to significantly contribute to VTE research.