Polarization-diversity optical coherence tomography retinal imaging of laser-induced choroidal neovascularization in small animal models

This preclinical in-vivo study uses polarization-diversity optical coherence tomography to identify features in laser-induced CNV small animal models, wild-type and Granzyme-B knockout mice, replicating wet AMD. The preliminary results show smaller affected areas in Granzyme-B knockout mice, potentially serving as an early biomarker for AMD. The study proposes that molecular-specific retinal imaging could provide additional information for further investigation of multiple retinal diseases.