Evaluating the Cerebral Alterations Induced by High-Definition Transcranial Direct Current Stimulation Over the Right Ventrolateral Prefrontal Cortex in the Three-Dimensional Attention

Currently, three-dimensional (3D) virtual reality (VR) exists technical limitations, which always induces mind-wandering and impedes VR's more widespread applications. In the previous study, we have confirmed that high-definition direct current stimulation in the right ventrolateral prefrontal cortex could significantly enhance this regional neural arousal and effectively ameliorate the sustained attentional capacity of participants in the 3D VR. However, the after-effects of electrical modulation on the holistic neural connectivity are still not clarified. In this study, we further analysed the electroencephalography recordings during the 3D attentional paradigm using graph theory to explore the HD-tDCS-induced overall cerebral topological alterations.