Modelling of Gaussian and Bessel Laser Beams Sharp Focused Into Complex Tissue-Like Scattering Medium with the Helmholtz Equation Approximation

The major challenge of optical imaging is to overcome the effects of strong light scattering of biological tissues that seriously limits the desired spatial resolution. In this relation in current practice of tissue optical imaging there is always a compromise between the depth of visualization and spatial resolution [1]. As a result, the development of high-resolution optical imaging requires a preliminary evaluation of sharpness of the wave-front of laser beams focusing into biological tissue.