Miniature Mass Spectrometers for On-Site Chemical Analysis

The miniaturization of mass spectrometers is a fast- growing new direction for the mass spectrometry (MS), enabling the transition of MS from laboratory to point of sample collection and and from experts to novice end users. During the past two decades, some major efforts have been put into this field which led significant advancements in both instrumentation as well as application. Here, we review the recent development in MS miniaturization and highlight the state-of-the-art systems as well as new technologies allowing some new capabilities for chemical and biological analysis.