Human Age Prediction Based on Brain MRI Using Density-Based Regression

In this paper, we have applied a density-based regression technique to predict the age of a human brain based on Magnetic Resonance Images. We propose four different multivariate discrete distributions to accommodate different mean-covariance and correlation structures, given the challenging nature of medical datasets. Then, we use a novel Minorization-Maximization framework to address the issue of high dimensional optimization. Finally, to handle the time and memory requirements of processing large amounts of high-resolution images, we have adopted a real-time framework, where the learning behavior is gradually improved as new data become available.