Correlation of 99mTc-MAG3 Renogram Imaging Paramaters for Renal Hydronphrotic Cases

Kidney obstruction exists acutely due to calculi, blood clots, tumors etc. leading to several renal colic with symptoms of flank pain, nausea, vomiting, and fever. Diuretic renal imaging is a safe procedure for the assessment of renal functioning and difference between nonobstructive and obstructive reasons of renal or ureteral enlargement. Radiotracer
^99m
Tc-MAG3 is chosen for pediatric patients with reduced function and supposed renal blockade, due to its added efficient extraction. The radiotracer
^99m
Tc-MAG3 excretion is greatly associated with the effective renal plasma flow (ERPF). Renal radio tracer transit activity period is needed in identification of renal obstruction stages which is associated with terms like renal hydronephrosis, Pelvic-ureteric Junction i.e. PUJ obstruction, pyeloplasty procedures etc. For measuring renal radio tracer transit period, radiotracer like DTPA/MAG3 etc. doesn't affect as all passed from the kidney through the urine flow. Valuations of renal function are beneficial in recognizing the presence of renal infection, observing the response of kidneys to medicines, and determining the growth of renal disease.
^99m
Tc-MAG3 scan supports to discriminate PUJ obstruction from multicystic kidney and regulate the level of kidney blockade. The key objective of this research study was to define correlation among renogram parameters maximum peak time
$(\mathbf{T}_{\mathbf{MAX}})$
, half of peak time
$(\mathbf{T}_{\mathbf{1}/\mathbf{2}})$
and ERPF with
^99m
Tc-MAG3 static as well as dynamic renal nuclear scintigraphy. For this project, the belongings of age, gender, whole renal system and stages of obstruction levels of 46 subjects were included and found evident correlations between renal measuring function parameters representing occurrences of pelvic hydronephrosis i.e. renal obstruction in left and/or right kidneys.