1. INTRODUCTION
Peripheral blood oxygen saturation (SpO2) is the ratio of oxygenated hemoglobin (HbO2) with respect to total hemoglobin, indicating the levels of oxygen supply in the blood. Oxygen saturation is an essential physiological parameter in the treatment of chronic cardiovascular and respiratory diseases. Especially in patients infected with COVID-19, it has been reported that hypoxemia can occur before breathing difficulties are observed [1], [2]. Therefore, continuous SpO2 monitoring is becoming increasingly important. SpO2 is usually measured using a pulse oximeter attached to the fingertip. However, contact-based pulse oximeters can cause discomfort, increase the risk of infection, and are not suitable for continuous monitoring. In addition, they have not been widely used in households. Recently, non-contact SpO2 estimation methods using facial or hand videos have been proposed [3] –[14], which may enable measurement using a tablet or smartphone. These video-based methods enable remote monitoring of SpO2 in video meetings and telemedicine scenarios.