Interpretation of Correlation Among Renal Obstruction Detecting Parameters Using 99mTc-DTPA Renal Diuretic Scintigraphy

Renal obstruction is a blockage that results in building up urine in the kidney. Due to this obstruction kidneys swells and hence urine cannot excrete through the body. Diagnose of renal hydronephotic level can be done by checking how well the kidneys are functioning and by inspecting the kidneys fill and void into the bladder. Thus, renal scintigraphy using radioisotope 99mTc- DTPA test is suggested that measures renal obstruction’s severity (i.e. hydronephrosis) by diagnosing radio tracer’s transit time renal parameters like peak time (TMAX), half peak time $(\mathrm{T}_{1/2)},(20$Min/Peak), 20Min/3Min and glomerular filtration rate of each kidney.These parameters are derived from the time activity curve using dual head gamma camera. This analysis was accomplished using 72 patients(with age ranging from 1 to 65 years) reported as hydronephrotic case including 37 patients with left kidney hydronephrosis and 35 patients with right kidney hydronephrosis and obtained a statistical relation among renal parameters and proved a significant effects of the obstruction severity on GFR values. Results of correlation among renal parameters found significantly positive and directly proportional with not only the levels of renal obstruction but also GFR.