Wafer Scale Multilayer Graphene Based Brain Probes by Spin-Spraying Methods for Magnetic Resonance Imaging

This paper proposes a convenient method for wafer scale multilayer graphene preparation by spin-spraying. Combining with the microfabrication process, graphenebased brain probes were acquired with graphene as both conducting traces and electrodes. Compared with metal ones, graphene electrodes show a nearly twelve-fold reduction in impedance and enhanced charge storage capacity, which is favorable for signal recording and brain stimulation. Specifically, they exhibit excellent biocompatibility, allowing safe implantation in the brain. Moreover, both simulations and in vitro experiments confirm their low artifacts during magnetic resonance imaging. Our studies provide a novel method for the fabrication of MR-safe probes.