Reactive Oxygen Species (ROS) Sensing- A Nanoscale Transistorized Approach

Reactive oxygen species (ROS) when under physiological equilibrium (equal production of in vivo antioxidants) controls the cellular signalling but due to non equilibrium in metabolism and respiration burst excess ROS are produced that has deleterious effect on human health. The elevated ROS level puts signatory contribution on cardiovascular, neurodegenerative diseases, inflammation, cancer cell proliferation etc. Therefore detection of ROS is important for healthy being. Thus the detection of ultra low ROS is a challenging issue. Field Effect Transistor based ROS detection provides accurate and ultra- measurement of sensitivity. This present review enumerates the evolution of different FET especially organic field effect transistor (OFET) based ROS sensor in a systematic approach. The review work will be helpful to researchers to find out the drawbacks of present FET based ROS sensor and to develop efficient sensor for theranostic applications.