A low power CMOS biopotentiostat in a low-voltage 0.13 µm digital technology

A biopotentiostat amplifier, for in-vivo applications, has been designed using a low-voltage low-power technology of 0.13 mum@1.2 V. The purpose of the designed bio-amplifier is oriented to sense the capacitive variations of electrochemical biosensor experiments at low frequencies. The designed amplifier seeks to function with a very small power consumption and occupies a very small area, compared with other designs, looking for an in-vivo application. It occupies an area of 327 mum times 260 mum, and has an average power consumption of 51.2 muW. The performance of the bio-amplifier has been simulated and experimentally validated.